Pathways Biology

NIBR focuses on core signaling pathways as an organizing principle to further understanding of disease mechanisms and identify novel targets relevant to disease. A diverse set of approaches, including chemical genetics, molecular genetics and molecular profiling ('omics') is applied across research topics including human genetics, regenerative medicine, mitochondrial function, proteostatis pathways, and a variety of human diseases.

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Building brain organoids to shed light on disease


Three-dimensional clusters of human neurons could allow scientists to watch neurological diseases develop in the lab.
Image credit: Max Salick/NIBR

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